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C-176
Item number: LKT-C000076.100
C-176 is a covalent inhibitor of STING. SMILES: C1=CC(=CC=C1NC(=O)C2=CC=C(O2)[N+](=O)[O-])I
| Keywords: | STING Inhibitor C-176, C176, C 176, N-(4-iodophenyl)-5-nitrofuran-2-carboxamide |
| Application: | STING antagonist |
| CAS | 314054-00-7 |
| MW: | 358.09 D |
From 84.00€
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C-176
Item number: TGM-T5154-100mg
Description: C-176 (STING inhibitor 1) is a STING inhibitor with selectivity and blood-brain barrier permeability. C-176 inhibits STING-mediated IFNbeta production and possesses anti-inflammatory activity. Target: STING. Smiles: [O-][N+](=O)c1ccc(o1)C(=O)Nc1ccc(I)cc1. References: Haag SM, et al. Targeting STING with...
| Keywords: | STING inhibitor 1, C176 |
| Application: | Covalent STING inhibitor |
| CAS | 314054-00-7 |
| MW: | 358.09 D |
From 31.00€
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C-176
Item number: Cay25859-10
C-176 is a covalent inhibitor of stimulator of interferon genes (STING). It selectively reduces STING-, but not RIG-I or TBK1-, mediated IFN-beta reporter activity in HEK293 cells when used at concentrations ranging from 0.01 to 5 µM. C-176 reduces serum levels of type-I interferons (IFNs) and cardiac inflammation...
| Keywords: | N-(4-iodophenyl)-5-nitro-2-furancarboxamide |
| Application: | Covalent STING inhibitor |
| CAS | 314054-00-7 |
| MW: | 358.1 D |
From 55.00€
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