3 products were found matching "313967-18-9"!
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FLI-06
Item number: Cay21272-5
FLI-06 is a first-of-its-kind inhibitor of Notch signaling (EC50 = 2.3 µM) that acts upstream of alpha-secretase and beta-secretase cleavage. It disrupts the intracellular trafficking and processing of the Notch signaling pathway, inhibiting general secretion at a stage before exit from the endoplasmic reticulum...
| Keywords: | 1,4,5,6,7,8-hexahydro-2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-3-quinolinecarboxylic acid, cyclohexyl ester |
| Application: | Notch signaling inhibitor |
| CAS | 313967-18-9 |
| MW: | 438.5 D |
From 122.00€
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FLI-06
Item number: LKT-F4432.1
Dihydropyridine, gamma-secretase inhibitor.
| Keywords: | 1,4,5,6,7,8-Hexahydro-2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-3-quinolinecarboxylic acid cyclohexyl ester |
| Application: | Dihydropyridine, gamma-secretase inhibitor |
| CAS | 313967-18-9 |
| MW: | 438.52 D |
From 87.00€
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FLI-06
Item number: TGM-T3075-100mg
Description: FLI-06 is a Notch signaling inhibitor (EC50: 2.3 µM). Target: Gamma-secretase. Smiles: CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c1ccc(cc1)[N+]([O-])=O)C(=O)OC1CCCCC1. References: Krämer A, et al. Nat Chem Biol. 2013, 9(11), 731-738.
| Keywords: | FLI 06 |
| Application: | Notch signaling inhibitor |
| CAS | 313967-18-9 |
| MW: | 438.52 D |
From 30.00€
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