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4-hydroxy Estrone
4-hydroxy Estrone

Item number: Cay33696-1

4-hydroxy Estrone is a metabolite of the endogenous estrogen estrone (Cay-10006485). It is formed from estrone primarily by the cytochrome P450 (CYP) isoforms CYP1B1, CYP1A2, and CYP1A1. 4-hydroxy Estrone (5 µM) induces nuclear translocation of phosphorylated p53 and is protective against glutamate-induced oxidative...
Keywords: 4-OHE1, 3,4-dihydroxy-estra-1,3,5(10)-trien-17-one
Application: Estrone metabolite
CAS 3131-23-5
MW: 286.4 D
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