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Item number: TGM-T11831-100mg

Description: LDN-27219 is a potent hTGase inhibitor with IC50 of 0.6 uM. Target: Others. Smiles: NNC(=O)CSc1nc2scc(-c3ccccc3)c2c(=O)n1-c1ccccc1. References: Case A, et al. Kinetic analysis of the interaction of tissue transglutaminase with a nonpeptidic slow-binding inhibitor. Biochemistry. 2007 Jan 30,46(4):1106-15.

Application:	Tansglutaminase 2 (TG2) inhibitor
CAS	312946-37-5
MW:	408.5 D

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LDN-27219

Item number: Cay32975-1

LDN-27219 is an inhibitor of tissue transglutaminase 2 (TG2, IC50 = 0.25 µM) that promotes its closed conformation. LDN-27219 induces relaxation of isolated rat mesenteric arteries precontracted with the thromboxane receptor agonist U-46619 (Cay-16450) in a concentration-dependent manner, an effect that can be...

Keywords:	2-[(3,4-dihydro-4-oxo-3,5-diphenylthieno[2,3-d]pyrimidin-2-yl)thio]-acetic acid, hydrazide (ACl)
Application:	Tansglutaminase 2 (TG2) inhibitor
CAS	312946-37-5
MW:	408.5 D

From 44.00€ *

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