Hygromycin B is an aminoglycoside antibiotic that has been found in S. hygroscopicus. It is active against E. coli (MIC = 150 µg/ml) and cytotoxic to both prokaryotic and eukaryotic cells via inhibition of protein synthesis. Hygromycin B has commonly been used in molecular and cell biology applications to select for...

It is an antibiotic from Streptomyces hygrosxopicus. It is a preferential translation inhibitor in virus-infected cells. The inhibition of protein synthesis is a consequence of a complex formation of the antibiotic with the ribosomal sub unit of the 70S ribosome that induces a localized conformational change.

Hygromycin B is an aminoglycosidic antibiotic which inhibits protein synthesis in bacteria, fungi and mammalian cells and is used to select prokaryotic and eukaryotic cells that have been transfected with the Hygromycin gene (hyg, hph, HMA, HM+). Source: Streptomyces hygroscopicus , Purity (HPLC): > 76%, Bioassay:...