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Indacaterol
Item number: Cay20070-50
Indacaterol is a long-acting and selective beta2-adrenergic receptor (beta2-AR) agonist (EC50 = 8.71 nM for increasing intracellular cAMP levels in vitro). It is selective for beta2-ARs over beta1- and beta3-ARs (Kis = 43.6, 616.6, and 3,311.3 nM, respectively). Indacaterol inhibits bronchoconstriction induced by...
| Keywords: | QAB149, 5-[(1R )-2-[(5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-hydroxy 2(1H )-quinolinone |
| Application: | beta2-Adrenergic receptor agonist |
| CAS | 312753-06-3 |
| MW: | 392.5 D |
From 73.00€
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Indacaterol
Item number: TGM-T2320-1mL
Description: Indacaterol (Onbrez, Arcapta) is a beta2-Adrenergic Agonist. The mechanism of action of indacaterol is as an Adrenergic beta2-Agonist. Target: Adrenergic Receptor. Smiles: CCc1cc2CC(Cc2cc1CC)NC[C@H](O)c1ccc(O)c2[nH]c(=O)ccc12. References: Battram, C., et al., In vitro and in vivo pharmacological...
| Application: | Targets adrenergic receptor beta-2 (ADRB2) |
| CAS | 312753-06-3 |
| MW: | 392.49 D |
From 41.00€
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