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Item number: TGM-T8527-100mg

Description: CPYPP is an inhibitor of DOCK2-Rac1 interaction. CPYPP binds to DOCK2 DHR-2 domain and inhibits the guanine nucleotide exchange factor (GEF) activity of DOCK2DHR-2 for Rac1 in a dose-dependent manner(IC50 : 22.8 µM). CPYPP also inhibits DOCK180, DOCK5 and less DOCK9. Target: Others. Smiles:...

Application:	DOCK2 / DOCK5 / DOCK180 inhibitor
CAS	310460-39-0
MW:	324.76 D

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CPYPP

Item number: Cay17386-10

CPYPP is an inhibitor of the Rac activators dedicator of cytokinesis 2 (DOCK2, IC50 = 22.8 µM for DOCK2 guanine nucleotide exchange factor (GEF) activity), DOCK5, and DOCK180. It is selective for these DOCK-A subfamily proteins over the DOCK-D subfamily member DOCK9. CPYPP (100 µM) prevents chemokine-induced Rac...

Keywords:	4-[3-(2-chlorophenyl)-2-propen-1-ylidene]-1-phenyl-3,5-pyrazolidinedione
Application:	DOCK2 / DOCK5 / DOCK180 inhibitor
CAS	310460-39-0
MW:	324.8 D

From 94.00€ *

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