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Item number: Cay42130-1

A USP22 inhibitor, increases the levels of ubiquitinated Foxp3, a target of Usp22, in primary mouse Tregs at 10, 15, or 20 µM, reduces tumor volume and increases intratumoral levels of CD4+CD8+ T cells in an LLC1 murine lung cancer model at 20 mg/kg per day for five days. Formulation: A solid. InChI:...

Keywords:	Ubiquitin-specific Protease 22 Inhibitor 1, Ubiquitin-specific Protease 22-IN-1, Ubiquitin-specific Protease 22i-S02,...
Application:	USP22 inhibitor
CAS	309735-96-4
MW:	338.4 D

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USP22-IN-1

Item number: TGM-T73151-100mg

Description: USP22-IN-1 is a ubiquitin-specific peptidase 22 (USP22) inhibitor that can be used to treat proliferative diseases or cancer. Target: DUB. Smiles: N#Cc1c2CCCCc2c(Nc2ccccc2)n2c3ccccc3nc12. References: Montauti E, et al. A deubiquitination module essential for Treg fitness in the tumor microenvironment....

CAS	309735-96-4
MW:	338.41 D

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