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Item number: Cay17768-5

SMER28 is a small-molecule enhancer (SMER) of autophagy that increases autophagosome synthesis and enhances clearance of aggregate-prone substrates, including those relevant to Huntington's, Parkinson's, and Alzheimer's diseases. SMER28 induces clearance of amyloid-beta (Abeta) peptides and the amyloid precursor...

Keywords:	6-bromo-N-2-propen-1-yl-4-quinazolinamine
Application:	Autophagy inducer, small-molecule enhancer (SMER)
CAS	307538-42-7
MW:	264.1 D

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SMER28

Item number: TGM-T3155-100mg

Description: SMER28 is a small-molecule enhancer (SMER) of autophagy, inducing autophagy independently of rapamycin in mammalian cells via an mTOR-independent mechanism and prevented the accumulation of amyloid beta peptide. Target: Autophagy. Smiles: BrC1=CC=C2N=CN=C(NCC=C)C2=C1. References: Tian Y, et al. FASEB J....

CAS	307538-42-7
MW:	264.12 D

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