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CFTR Inhibitor-172
Item number: Cay15545-5
The cystic fibrosis (CF) gene encodes a cAMP-regulated chloride channel, the CF transmembrane conductance regulator (CFTR). CFTR inhibitor-172 is a thiazolidinone that selectively blocks the CFTR channel (Ki = 300 nM) in a voltage-independent manner. It appears to directly modulate the gating of chloride at the...
| Keywords: | CFTR(inh)-172, Cystic Fibrosis Transmembrane Conductance Regulator Inhibitor 172,... |
| Application: | CFTR blocker |
| CAS | 307510-92-5 |
| MW: | 409.4 D |
From 126.00€
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CFTR(inh)-172
Item number: TGM-T2355-1mg
Description: CFTR(inh)-172 (CFTR Inhibitor-172) is a voltage-independent, selective CFTR inhibitor. Target: Autophagy, CFTR. Smiles: OC(=O)c1ccc(\C=C2/SC(=S)N(C2=O)c2cccc(c2)C(F)(F)F)cc1. References: Ma T, et al. J Clin Invest. 2002, 110(11), 1651-1658.
| Keywords: | CFTRinh172, CFTRinh 172, CFTR Inhibitor-172, CFTRinh-172 |
| Application: | CFTR blocker |
| CAS | 307510-92-5 |
| MW: | 409.4 D |
From 30.00€
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