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GW 1100
GW 1100

Item number: Cay10008908-5

GPR40 (free fatty acid receptor 1, FFAR1) is a G protein-coupled receptor (GPCR) that is activated by saturated and unsaturated long chain fatty acids. It is thought to play a role in the potentiation of insulin secretion by fatty acids in a glucose-sensitive manner. GW 1100 is a selective antagonist of...
Keywords: 4-[5-[(2-ethoxy-5-pyrimidinyl)methyl]-2-[[(4-fluorophenyl)methyl]thio]-4-oxo-1(4H)-pyrimidinyl]-benzoic acid, ethyl ester
Application: GPR40 antagonist
CAS 306974-70-9
MW: 520.6 D
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GW-1100
GW-1100

Item number: TGM-T15448-5mg

Description: GW-1100 is a selective GPR40 and FFAR1 antagonist for the study of diabetes and metabolic diseases. Target: GPR. Smiles: CCOC(=O)c1ccc(cc1)-n1cc(Cc2cnc(OCC)nc2)c(=O)nc1SCc1ccc(F)cc1. References: Stoddart LA, et al. Uncovering the pharmacology of the G protein-coupled receptor GPR40: high apparent...
Keywords: GW1100, GW 1100
Application: GPR40 antagonist
CAS 306974-70-9
MW: 520.58 D
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