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Esculetin
Esculetin

Item number: Cay19286-1

Esculetin is a coumarin that has been found in Euphorbia and has diverse biological activities. It inhibits 5-lipoxygenase (5-LO) and 12-LO (IC50s = 4 and 2.5 µM, respectively), as well as the histone demethylase jumonji AT-rich interactive domain 1B (JARID1B, IC50 = 4.6 µM). Esculetin is active against B. cereus,...
Keywords: 6,7-Dihydroxycoumarin, Aesculetin, Cichorigenin, NSC 26427, 6,7-dihydroxy-2H-1-benzopyran-2-one
Application: Iron chelator, Iron-containing enzyme inhibitor, Apoptosis inducer, Antioxidant
CAS 305-01-1
MW: 178.1 D
From 43.00€ *
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Esculetin
Esculetin

Item number: LKT-E7309.1

A lipoxygenase inhibitor. Also a potent chemopreventive agent capable of reducing oxidative stress in liver, inhibiting carcinogen DNA binding in human bronchial epithelial cells and inducing reduced glutathione in buffalo rat liver cells.
Keywords: Aesculetin, esculetin, 6,7-dihydroxycoumarin, cichorigenin
Application: LO inhibitor
CAS 305-01-1
MW: 178,14 D
From 100.00€ *
Review