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Yaddle1
Yaddle1

Item number: Cay43431-10

Yaddle1 is an agonist of Piezo1 and a derivative of Yoda1 (Cay-21904). It induces calcium influx in a reporter assay using HEK293A cells expressing human Piezo1 (EC50 = 0.4 µM). Yaddle1 (15 µM) induces calcium influx in primary human CD4+ T cells, which express Piezo1, and does not decrease the viability of isolated...
Keywords: 2-[5-[[[2-chloro-6-(trifluoromethyl)phenyl]methyl]thio]-1,3,4-oxadiazol-2-yl]-pyrazine
Application: Piezo1 agonist
CAS 3041134-13-5
MW: 372.75 D
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