2 products were found matching "303727-31-3"!
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L-779450
Item number: TGM-T1953-100mg
Description: L-779450, an effective, ATP-competitive Raf kinase inhibitor (IC50: 10 nM) , displays > 7, > 30 and > 70-fold selectivity over p38alpha, GSK3beta and Lck respectively. Target: Autophagy, Raf. Smiles: Oc1cc(ccc1Cl)-c1[nH]c(nc1-c1ccncc1)-c1ccccc1. References: Shelton JG, et al. Leukemia. 2003...
| Keywords: | L 779450 |
| Application: | Raf kinase inhibitor |
| CAS | 303727-31-3 |
| MW: | 347.8 D |
From 42.00€
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L-779,450
Item number: Cay17807-1
L-779,450 is an ATP-competitive B-Raf inhibitor (IC50 = 10 nM, Kd = 2.4 nM) that displays >7, >30, and >70-fold selectivity over p38alpha, GSK3beta, and Lck, respectively. It has been shown to inhibit cell proliferation both in B-Raf mutated and wild-type melanoma cell lines, as well as to enhance tumor necrosis...
| Keywords: | Raf Kinase Inhibitor IV, 2-chloro-5-[2-phenyl-4-(4-pyridinyl)-1H-imidazol-5-yl]-phenol |
| Application: | Raf kinase inhibitor |
| CAS | 303727-31-3 |
| MW: | 347.8 D |
From 44.00€
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