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Item number: Cay42704-1

BC13 is a dual inhibitor of cyclin-dependent kinase 6 (Cdk6) and bromodomain-containing protein 4 (BRD4, IC50s = 36. 234. and 137. nM for Cdk6 and BRD4 bromodomain 1 (BD1) and BD2), respectively). It is selective for Cdk6 over Cdk1-Cdk5 at 500 nM and for BD1 and BD2 in BRD4 over those in BRD2 and BRD3 (IC50s =...

Keywords:	8-cyclopentyl-2-[2-[4-(3,4-dihydro-5,7-dimethoxy-4-oxo-2-quinazolinyl)benzoyl]-2,7-diazaspiro[3.5]non-7-yl]-5-methyl-pyrid...
Application:	Cdk6 / BRD4 dual inhibitor
CAS	3036645-03-8
MW:	661.76 D

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