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Item number: Cay45518-1

Mz325 is a dual inhibitor of histone deacetylase 6 (HDAC6) and sirtuin 2 (SIRT2, IC50s = 0.043 and 0.32 µM, respectively, in a cell-free assay). Mz325 is a heterobifunctional molecule that contains an HDAC6 inhibitor conjugated to a SIRT2 inhibitor via a triazole linker. It is selective for HDAC6 and SIRT2 over...

Keywords:	N-butyl-4-[[3-[[2-[[2-[(4,6-dimethyl-2-pyrimidinyl)thio]acetyl]amino]-5-thiazolyl]methyl]phenoxy]methyl]-N-[[4-[(hydroxyam...
Application:	HDAC6 / SIRT2 dual inhibitor
CAS	3032670-12-2
MW:	771.96 D

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