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TAK-715
Item number: TGM-T6150-100mg
Description: TAK-715 is a p38 MAPK inhibitor for p38alpha. Target: JNK, Casein Kinase, p38 MAPK. Smiles: CCc1nc(c(s1)-c1ccnc(NC(=O)c2ccccc2)c1)-c1cccc(C)c1. References: Miwatashi S, et al. J Med Chem, 2005, 48(19), 5966-5979.
| Application: | MAPK14 / p38 alpha inhibitor |
| CAS | 303162-79-0 |
| MW: | 399.51 D |
From 34.00€
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TAK-715
Item number: SYN-1087-M005
Soluble in DMSO or ethanol. TAK-715 is a potent specific inhibitor of the p38alpha MAP kinase with an IC(50) of 7.1nM. It is approximately 30-fold more selective for p38alpha over p38beta. It shows no inhibition of p38gamma/delta. Target: p38 , Kinase Group: CMGC , Substrate: Serine-Threonine
| Keywords: | TAK715 |
| Application: | p38 alpha inhibitor |
| CAS | 303162-79-0 |
| MW: | 399,5 D |
From 108.00€
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TAK-715
Item number: Cay26170-5
TAK-715 is an inhibitor of p38alpha MAPK (IC50 = 7.1 nM). It is selective for p38alpha over p38beta (IC50 = 200 nM), as well as over p38gamma/delta, JNK, ERK1, IKKbeta, MEKK1, and TAK1 (IC50 = >10 µM for all) but also inhibits casein kinase Idelta (CK1delta) and CK1epsilon. It inhibits TNF-alpha release induced by...
| Keywords: | N-[4-[2-ethyl-4-(3-methylphenyl)-5-thiazolyl]-2-pyridinyl]-benzamide |
| Application: | MAPK14 / p38 alpha inhibitor |
| CAS | 303162-79-0 |
| MW: | 399.5 D |
From 111.00€
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