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Item number: Cay11992-1

Ro 67-4853 is a positive allosteric modulator of metabotropic glutamate 1 receptors (mGluR1), enhancing glutamate-induced calcium signaling through both the human and mouse mGlu1a receptors (pEC50 = 7.16). While only mildly potentiating mGluR5 signaling, this compound is without effect at mGluR2, mGluR4, or mGluR8,...

Keywords:	N-(9H-xanthen-9-ylcarbonyl)-carbamic acid, butyl ester
Application:	mGluR1 modulator
CAS	302841-89-0
MW:	325.4 D

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