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Ro 67-4853
Item number: Cay11992-1
Ro 67-4853 is a positive allosteric modulator of metabotropic glutamate 1 receptors (mGluR1), enhancing glutamate-induced calcium signaling through both the human and mouse mGlu1a receptors (pEC50 = 7.16). While only mildly potentiating mGluR5 signaling, this compound is without effect at mGluR2, mGluR4, or mGluR8,...
| Keywords: | N-(9H-xanthen-9-ylcarbonyl)-carbamic acid, butyl ester |
| Application: | mGluR1 modulator |
| CAS | 302841-89-0 |
| MW: | 325.4 D |
From 49.00€
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Ro 67-4853
Item number: TGM-T23248-1mg
Description: Ro 67-4853 is a selective mGluR1 positive allosteric modulator, enhancing the response to the agonist (S)-3,5-dihydroxyphenylglycine (DHPG) in anesthetized rats through iontophoretic administration. Target: GluR. Smiles: O=C(OCCCC)NC(=O)C1C=2C=CC=CC2OC=3C=CC=CC31
| Keywords: | Ro 674853 , Ro67-4853 |
| Application: | mGluR1 modulator |
| CAS | 302841-89-0 |
| MW: | 325.36 D |
From 56.00€
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