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Lipid TG4C
Lipid TG4C

Item number: Cay42941-1

Lipid TG4C is an ionizable cationic glycerolipid (pKa = 6.71) that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vivo. LNPs containing lipid TG4C and encapsulating mRNA encoding human erythropoietin (EPO) increase serum EPO levels in mice. Nebulized administration of LNPs...
Keywords: hexanedioic acid, 1,1'-[2-[4-(dimethylamino)-1-oxobutoxy]-1,3-propanediyl] 6,6'-bis(1-octylnonyl) ester
Application: Ionizable cationic glycerolipid, LNP formation
CAS 3028336-07-1
MW: 938.43 D
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