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Item number: Cay18462-10

Fms-like tyrosine kinase (FLT3) is a cell-surface receptor with important roles in stem cell development, hematopoiesis, and cancer. FLT3 Inhibitor is a cell-permeable, ATP-competitive inhibitor of FLT3 (IC50 = 27 nM) that blocks the proliferation of myelomonocytic leukemia MV4-11 cells (IC50 = 0.41 µM). It is...

Keywords:	Fms-like Tyrosine Kinase Inhibitor, TCS 359,...
Application:	CD135 inhibitor
CAS	301305-73-7
MW:	360.4 D

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TCS 359

Item number: TGM-T6138-100mg

Description: TCS 359 (FLT3 Inhibitor) is a potent FLT3 inhibitor with IC50 of 42 nM. Target: FLT. Smiles: COc1ccc(cc1OC)C(=O)Nc1sc2CCCCc2c1C(N)=O. References: Raymond J. Patch, et al. Bioorg Med Chem Lett, 2006, 16(12), 3282-3286.

Keywords:	FLT3 Inhibitor
Application:	CD135 inhibitor
CAS	301305-73-7
MW:	360.43 D

From 30.00€ *

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