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ESI-08
Item number: Cay43208-10
ESI-08 is an inhibitor of exchange protein activated by cAMP 2 (Epac2, IC50 = 8. µM).. Solulibility: Acetonitrile: Slightly Soluble: 0.1-1 mg/mL: Water: Slightly Soluble: 0.1-1 mg/mL.
| Keywords: | 4-cyclohexyl-2-[[(2,5-dimethylphenyl)methyl]thio]-1,6-dihydro-6-oxo-5-pyrimidinecarbonitrile |
| Application: | Epac2 (RAPGEF4, Rap guanine nucleotide exchange factor 4) inhibitor |
| CAS | 301177-43-5 |
| MW: | 353.48 D |
From 190.00€
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ESI-08
Item number: TGM-T11234-10mg
Description: ESI-08 is an effective antagonist of EPAC2 with an IC50 of 8.4 µM. ESI-08 selectively blocks cAMP-induced EPAC activation but not cAMP-mediated PKA activation. Target: cAMP. Smiles: Cc1ccc(C)c(CSc2nc(C3CCCCC3)c(C#N)c(=O)[nH]2)c1. References: Chen H, et al. 5-Cyano-6-oxo-1,6-dihydro-pyrimidines as potent...
| CAS | 301177-43-5 |
| MW: | 353.48 D |
From 52.00€
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