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(±)-4-CMTB
Item number: Cay29680-5
(±)-4-CMTB is a positive allosteric modulator of free fatty acid receptor 2 (FFAR2/GPR43) with an EC50 value of 0.42 µM for [35S]GTPgammaS binding to 293 T-REx cell membranes expressing the human receptor. It selectively induces ERK1/2 phosphorylation in 293 T-REx cells expressing human FFAR2, but not FFAR1 or...
| Keywords: | 4-chloro-alpha-(1-methylethyl)-N-2-thiazolyl-benzeneacetamide |
| Application: | FFAR2/GPR43 positive allosteric modulator |
| CAS | 300851-67-6 |
| MW: | 294.8 D |
From 174.00€
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4-CMTB
Item number: TGM-T8642-100mg
Description: 4-CMTB is a selective agonist of FFA2 and GPR43.It also is a positive allosteric modulator (pEC50=6.38). Target: GPR. Smiles: CC(C)C(C(=O)Nc1nccs1)c1ccc(Cl)cc1. References: Milligan G, Stoddart LA, Smith NJ. Agonism and allosterism: the pharmacology of the free fatty acid receptors FFA2 and FFA3. Br J...
| Application: | FFAR2/GPR43 positive allosteric modulator |
| CAS | 300851-67-6 |
| MW: | 294.8 D |
From 39.00€
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