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NKY80
Item number: Cay17777-5
NKY80 is a cell-permeable inhibitor of adenylyl cyclase (AC) that is selective for isoform AC5 over AC2 and AC3 (IC50s = 8.3 µM, 1.7 mM, and 132 µM, respectively in the presence of Gsalpha GTPgammaS-forskolin). It is a non-competitive inhibitor with respect to ATP (Cay-14498) and forskolin (Cay-11018) and tissue...
| Keywords: | Adenylyl Cyclase Type V Inhibitor, 2-amino-7-(2-furanyl)-7,9-dihydro-5(6H)-quinazolinone |
| Application: | Cell-permeable ADCY5 inhibitor |
| CAS | 299442-43-6 |
| MW: | 229.2 D |
From 110.00€
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NKY80
Item number: TGM-T16333-100mg
Description: NKY80 regulates the adenylyl cyclase catalytic activity in heart and lung tissues. NKY80 is a non-competitive inhibitor of adenylyl cyclase type V isoform (IC50s: 8.3 µM, 132 µM, and 1.7 mM for type V, III and II, respectively). Target: Adenylyl cyclase. Smiles: NC1=NC2=C(C=N1)C(=O)CC(C2)C1=CC=CO1....
| Keywords: | Adenylyl cyclase type V Inhibitor |
| Application: | Cell-permeable ADCY5 inhibitor |
| CAS | 299442-43-6 |
| MW: | 229.23 D |
From 38.00€
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