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Item number: Cay44283-1

RP 1664 is an inhibitor of polo-like kinase 4 (Plk4, IC50 = 3 nM). It induces centriole depletion in hTERT RPE-1 retinal pigment cells (EC50 = 0. µM). RP 1664 induces cytotoxicity in MCF-7 breast cancer cells (EC50 = 0. µM). It reduces tumor volume in a CAL-148 breast cancer mouse xenograft model when administered...

Keywords:	5-cyclopropyl-N2-(2,6-difluoro-4-(methylsulfonyl)phenyl)-N2-methyl-6-(1-methyl-1H-imidazol-4-yl)-N4-(5-methyl-1H-pyrazol-3...
Application:	Plk4 inhibitor
CAS	2980682-00-4
MW:	514.56 D

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