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Lipofermata
Lipofermata

Item number: TGM-T11854-100mg

Description: Lipofermata, a fatty acid transport protein (FATP) inhibitor, prevents lipid transport to melanoma cells and reduces their growth and invasion. Target: Antibacterial, Others. Smiles: Brc1ccc2NC(=O)C3(NN=C(S3)c3ccccc3)c2c1. References: Zhang M,et al. Adipocyte-Derived Lipids Mediate Melanoma Progression...
CAS 297180-15-5
MW: 360.23 D
From 55.00€ *
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Lipofermata
Lipofermata

Item number: Cay25869-10

Lipofermata is an inhibitor of fatty acid transport (IC50 = 4.84 µM in Caco-2 cells). It inhibits uptake of long- and very long-chain, but not medium-chain, fatty acids in mmC2C12, rnINS-1E, Caco-2, and HepG2 cells (IC50s = 3-6 µM). Lipofermata inhibits induction of BiP and CHOP, apoptosis, and lipid droplet...
Keywords: 5-bromo-5'-phenyl-spiro[3H-indole-3,2'(3'H)-[1,3,4]thiadiazol]-2(1H)-one
Application: Fatty acid transport inhibitor
CAS 297180-15-5
MW: 360.2 D
From 55.00€ *
Review
Lipofermata
Lipofermata

Item number: AG-CR1-3542-M010

Lipofermata is an inhibitor of fatty acid transport, blocking fatty acid transport protein 2 (FATP2), and was identified afterwards as a FATP1 inhibitor as well. Inhibition was specific for long and very long chain fatty acids but not medium (C6-C10) fatty acids in myocytes (mmC2C12), pancreatic beta cells...
Keywords: 5´-Bromo-5-phenyl-spiro[3H-1,3,4-thiadiazole-2,3´-indoline]-2´-one, CB16.2
Application: Fatty acid transport inhibitor
CAS 297180-15-5
MW: 360,2 D
From 77.00€ *
Review