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B32B3
B32B3

Item number: Cay16364-10

Virus protein R (Vpr) is a virion-associated protein expressed by lentiviruses, including HIV-1 and -2. It causes cell cycle arrest in infected cells by binding the mammalian Vpr-binding protein (VprBP) on the DDB1/CUL4 ubiquitin ligase complex. VprBP, also known as DDB1/CUL4-associated factor 1, acts as an adaptor...
Keywords: VprBP Inhibitor, 2-(5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-yl)hydrazone 1H-indole-3-carboxaldehyde
Application: Cell-permeable, ATP-competitive VprBP inhibitor
CAS 294193-86-5
MW: 347.4 D
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