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Item number: Cay44474-1

BI-2493 is an inhibitor of mutant K-Ras. It selectively decreases the proliferation of Ba/F3 cells expressing K-Ras containing a glycine-to-cysteine substitution at position 12 (K-RasG12C), K-RasG12D, or K-RasG12V (EC50s = 118, 52, and 81 nM, respectively) over Ba/F3 cells expressing H-Ras or N-Ras (EC50s = 2,359...

Keywords:	(4'S)-2'-amino-5,6,6',7'-tetrahydro-3-[2-[(2S)-2-methyl-1-piperazinyl]-4-pyrimidinyl]-spiro[1,2-benzisoxazole-7(4H),4'(5'H...
Application:	Mutant K-Ras inhibitor
CAS	2937344-16-4
MW:	461.59 D

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BI-2493

Item number: TGM-T72061-10mg

Description: BI-2493 is a highly selective pan-KRAS inhibitor and structural analog of BI-2865.BI-2493 exhibits antitumor activity and inhibits tumor cell growth and can be used in the study of cancerous diseases.BI-2493 is a highly selective pan-KRAS inhibitor and structural analog of BI-2865. Target: Ras. Smiles:...

CAS	2937344-16-4
MW:	461.58 D

From 595.00€ *

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