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Item number: Cay16021-100

Ciclopirox is an iron chelator, antifungal, and anticancer agent. It inhibits the iron-dependent enzyme hypoxia-inducible factor prolyl hydroxylase 2 (HIF-PH2, IC50 = 1.58 µM), an effect that is reduced in the presence of iron. It stabilizes hypoxia-inducible factor-alpha (HIF-1alpha) under normoxic conditions in...

Keywords:	HOE 296b, 6-cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridinone
Application:	Antifungal, Cell-permeable iron-chelating agent, EGLN1 inhibitor
CAS	29342-05-0
MW:	207.3 D

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