Upon reacting with amines and thiol compounds it generates the same fluorescent adducts as those of NBD-Cl. Compared with NBD-Cl, NBD-F is much more reactive, and should be more carefully stored.

Yellow to yellow with brown cast powder. Soluble in DMF. NBD fluoride is similar to NBD chloride except that the former is much more reactive toward amines. Both reagents are nonfluorescent until they react with primary or secondary amines to produce a fluorescent product. NBD chloride and NBD fluoride have been...