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PT-179
Item number: Cay43028-5
PT-179 is a molecular glue and ligand for the E3 ubiquitin ligase cereblon. It has been used in conjunction with the zinc finger degron SD40 to induce degradation of SD40-tagged proteins.. Solulibility: DMSO: Soluble: = 10 mg/ml: .
| Keywords: | 2-(2,6-dioxo-3-piperidinyl)-5-(4-morpholinyl)-1H-isoindole-1,3(2H)-dione |
| Application: | Molecular glue, cereblon ligand |
| CAS | 2924858-25-1 |
| MW: | 343.34 D |
From 127.00€
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PT-179
Item number: TGM-T84301-100mg
Description: PT-179 is a novel IMiD derivative, a molecular gel. Target: Molecular Glues. Smiles: O=C1C2=CC=C(C=C2C(=O)N1C3C(=O)NC(=O)CC3)N4CCOCC4. References: Mercer JAM,et al. Continuous evolution of compact protein degradation tags regulated by selective molecular glues. Science. 2024 Mar 15,383(6688):eadk4422.
| CAS | 2924858-25-1 |
| MW: | 343.33 D |
From 49.00€
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