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UCL-TRO-1938
UCL-TRO-1938

Item number: Cay39118-1

UCL-TRO-1938 is an allosteric activator of PI3Kalpha. It binds to PI3Kalpha in a surface plasmon resonance (SPR) assay (Kd = 36 µM) and induces PI3Kalpha activation in a cell-free assay when used at concentrations of 25 and 50 µM, an effect that can be reversed by the PI3Kalpha inhibitor BYL719 (Cay-16986)....
Keywords: 1-[7-[[2-[[4-(4-ethyl-1-piperazinyl)phenyl]amino]-4-pyridinyl]amino]-2,3-dihydro-1H-indol-1-yl]-ethanone
Application: Allosteric PI3Kalpha activator
CAS 2919575-27-0
MW: 456.6 D
From 42.00€ *
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UCL-TRO-1938
UCL-TRO-1938

Item number: TGM-T78092-10mg

Description: UCL-TRO-1938 is a subtype-selective PI3Kalpha allosteric activator with cardioprotective and neuroregenerative effects. UCL-TRO-1938 can induce cell proliferation and can be used to study diseases caused by abnormal PI3Kalpha metabolism. Target: PI3K. Smiles:...
Application: Allosteric PI3Kalpha activator
CAS 2919575-27-0
MW: 456.58 D
From 115.00€ *
Review