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Hymeglusin
Item number: Cay11899-1
Hymeglusin is a fungal beta-lactone antibiotic that inhibits HMG-CoA synthase (IC50 = 0.12 µM) by covalently modifying the active Cys129 residue of the enzyme. At a dose of 25 mg/kg, hymeglusin inhibits cholesterol biosynthesis in rats by 45%. Chiral studies indicate that the (2R,3R)-beta-lactone moiety of...
| Keywords: | Antibiotic 1233A, Antibiotic F 244, L 659,699,... |
| Application: | HMG-CoA synthase inhibitor, Antibiotic |
| CAS | 29066-42-0 |
| MW: | 324.4 D |
From 191.00€
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(R, R)-Hymeglusin
Item number: AG-CN2-0103-MM25
Beta-Lactone antibiotic, antibacterial and antifungal, specific and irreversible inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase in vitro and in vivo by covalently modifying the active Cys129 residue of the enzyme, mevalonate biosynthesis inhibitor
| Keywords: | 1233A, F-244, L-659-699 |
| Application: | HMG-CoA synthase inhibitor |
| CAS | 29066-42-0 |
| MW: | 324,4 D |
From 176.00€
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NEW
Hymeglusin
Item number: TGM-T27766-1mg
Description: Hymeglusin, A selective 3-hydroxy-3-methylglutaryl Coenzyme A (HMG-CoA) synthase 1 inhibitor, is also an antibiotic that reduces the expression level of BCL2 in HL-60 and KG-1 cells and can be used to study leukemia. Target: Antibiotic. Smiles:...
| Keywords: | L659,699, 1233A, L-659,699, F-244, L 659,699 |
| Application: | HMG-CoA synthase inhibitor |
| CAS | 29066-42-0 |
| MW: | 324.41 D |
723.00€
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