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Item number: Cay13863-10

Estrogen action is mediated through two estrogen receptor (ER) subtypes, ERalpha and ERbeta, which have distinct target tissue distributions and functional activities. Methylpiperidino pyrazole is an ER antagonist that is highly selective for ERalpha compared to ERbeta (Kis = 5.6 nM and 2.3 µM, respectively). It can...

Keywords:	MPP, 4-[1-(4-hydroxyphenyl)-4-methyl-5-[4-[2-(1-piperidinyl)ethoxy]phenyl]-1H-pyrazol-3-yl]-phenol
Application:	ERalpha antagonist
CAS	289726-02-9
MW:	469.6 D

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Methylpiperidino pyrazole

Item number: TGM-T21897-10mg

Description: Methylpiperidino pyrazole is an ERalpha inhibitor and can prevent the BPS-induced Rb phosphorylation and cell cycle progression. Target: Estrogen/progestogen Receptor. Smiles: Cc1c(-c(cc2)ccc2OCCN2CCCCC2)n(-c(cc2)ccc2O)nc1-c(cc1)ccc1O. References: Lin Z, et al. Bisphenol S promotes the cell cycle...

CAS	289726-02-9
MW:	469.57 D

From 198.00€ *

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