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Item number: Cay39387-1

JAK inhibitor 31 is an inhibitor of JAK2 (IC50 = 3.9 nM). It is selective for JAK2 over JAK3 (IC50s = 70 nM), as well as Aurora B kinase, VEGFR2, Abl1, and GSK3beta (IC50s = 0.441, 1.5, 21.37, and 50 µM, respectively), but does inhibit JAK1 and TYK2 (IC50s = 7 and 2.9 nM, respectively). JAK inhibitor 31 inhibits...

Keywords:	Janus-Associated Kinase Inhibitor 31,...
Application:	JAK2 inhibitor
CAS	2891469-99-9
MW:	398.5 D

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