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IBMX
IBMX

Item number: Cay13347-100

IBMX is a widely-used non-specific inhibitor of cyclic AMP and cyclic GMP phosphodiesterases (PDEs) (IC50 = 19, 50, 18, 13, 32, 7, and 50 µM for PDE1, PDE2, PDE3, PDE4, PDE5, PDE7, and PDE11, respectively). PDE8A, PDE8B, and PDE9 are insensitive to IBMX. By inhibiting PDEs, IBMX increases cellular cAMP and cGMP...
Keywords: 1-Methyl-3-Isobutylxanthine, Isobutylmethylxanthine, NSC 165960, SC-2964,...
Application: PDE inhibitor
CAS 28822-58-4
MW: 222.3 D
From 50.00€ *
Review
IBMX
IBMX

Item number: AG-CR1-3512-M500

Cell permeable protein kinase C (PKC) inhibitor. Inhibits also protein kinase A (PKA).
Keywords: 3-Isobutyl 1-methylxanthine, NSC 165960, EINECS 249-259-3
Application: Phosphodiesterase inhibitor
CAS 28822-58-4
MW: 222,3 D
From 121.00€ *
Review