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Item number: Cay12029-10

Rosuvastatin is an inhibitor of HMG-CoA reductase (IC50 = 5 nM). It inhibits cholesterol synthesis in isolated rat hepatocytes with an IC50 value of 0.16 nM. Rosuvastatin (10 mg/kg) reduces plasma total cholesterol, triglyceride, LDL-C, and oxidized LDL-C levels in Ldlr-/- mice fed a high-fat diet. It decreases the...

Keywords:	ZD 4522,...
Application:	HMG-CoA reductase inhibitor
CAS	287714-41-4
MW:	481.5 D

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