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Nigericin (sodium salt)
Item number: Cay11437-5
Nigericin is a lipophilic potassium ionophore that has been found in S. hygroscopicus. It mediates neutral antiport of potassium and proton ions across mitochondrial membranes. Nigericin (10 µM) induces T. gondii egress in infected human foreskin fibroblasts (HFFs). It also induces NOD-like receptor protein 3...
| Keywords: | NSC 292567,... |
| Application: | Metabolic studies |
| CAS | 28643-80-3 |
| MW: | 747 D |
From 77.00€
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Nigericin, sodium salt
Item number: AG-CN2-0020-M005
Isolated from Streptomyces hygroscopicus. Antibiotic. High affinity ionophore for monovalent cations such as H, K, Na, Pb2. Shows antibacterial (Gram-positive), antifungal, antitumor and antiviral activity. Disrupts membrane potential and Golgi apparatus in mitochondria. NLRP3/NALP3 activator. Signals through...
| Keywords: | Antibiotic K 178, Helexin C, Polyetherin A, BRN 1696755, Azalomycin M, Antibiotic X-464 |
| Application: | Ionophore |
| CAS | 28643-80-3 |
From 66.00€
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Nigericin sodium salt
Item number: CDX-N0094-M005
Nigericin is an antibiotic, used as a high affinity ionophore for monovalent cations such as H+, K+, Na+, Pb2+. It shows antibacterial (Gram-positive), antifungal, antitumor and antiviral activity and disrupts membrane potential of mitochondria. It sprimary use is as a NLRP3 activator in inflammasome research.
| Keywords: | Antibiotic X464, Azalomycin M, Polyetherin A, Antibiotic K178, Helexin C |
| Application: | Antibiotic |
| CAS | 28643-80-3 |
| MW: | 746,94 D |
From 87.00€
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Nigericin sodium
Item number: LKT-N3225.10
A potassium ionophore, found to induce cell death and promote the maturation and release of IL-1beta in lipopolysaccharide primed monocytes and macrophages. It also enhances rapamycin action.
| Application: | Metabolic studies |
| CAS | 28643-80-3 |
| MW: | 747 D |
From 85.00€
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