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Item number: Cay39922-1

TDI-11861 is an inhibitor of soluble adenylyl cyclase (sAC, IC50 = 3.3 nM), a bicarbonate-regulated cytosolic enzyme also known as AC10. It is selective for sAC over the transmembrane ACs (tmACs) AC1, AC2, AC5, AC8, and AC9 at 100 nM, a panel of 322 kinases (IC50s = >1,000 nM for all), and 46 other targets,...

Keywords:	(3R)-4-[2-[2-[[3-(2-amino-6-chloro-4-pyrimidinyl)-1-(difluoromethyl)-1H-pyrazol-4-yl]methyl]phenoxy]ethyl]-3-morpholinemet...
Application:	Soluble adenylyl cyclase inhibitor
CAS	2857049-72-8
MW:	494.9 D

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