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Bumetanide
Bumetanide

Item number: Cay14630-1

Bumetanide is an inhibitor of Na-K-2Cl cotransporter 1 (NKCC1, IC50 = 0.68 µM). It is selective for NKCC1 over NKCC2 (IC50 = 4 µM). Bumetanide is an agonist of G protein-coupled receptor 35 (GPR35, EC50 = 10 µM). It also inhibits various carbonic anhydrases. Bumetanide (0.1 mg/kg) increases urine flow and sodium and...
Keywords: PF 1593, Ro 10-6338, 3-(aminosulfonyl)-5-(butylamino)-4-phenoxy-benzoic acid
Application: NKCC1/2 inhibitor
CAS 28395-03-1
MW: 364.4 D
From 61.00€ *
Review
Bumetanide
Bumetanide

Item number: LKT-B8248.250

Bumetanide binds to Na-K-Cl co-transporter and inhibits its action.
Application: Metabolic studies
CAS 28395-03-1
MW: 364,42 D
From 156.00€ *
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Bumetanide
Bumetanide

Item number: AG-CR1-3543-G005

Bumetanide is a loop diuretic that is clinically used to treat congestive heart failure. Bumetanide also exhibits anxiolytic, neuroprotective and anti-epileptic/anticonvulsant activities. Bumetanide induces hyperpolarization in kidney cells, increasing whole-cell conductance and intracellular Ca2+ levels. Bumetanide...
Keywords: PF-1593, Ro 10-6338, 3-(Aminosulfonyl)-5-(butylamino)-4-phenoxybenzoic acid
Application: Na-K-Cl cotransporter inhibitor
CAS 28395-03-1
MW: 364,4 D
From 33.00€ *
Review