- Search results for 28395-03-1
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3 products were found matching "28395-03-1"!
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Item number: Cay14630-1
Bumetanide is an inhibitor of Na-K-2Cl cotransporter 1 (NKCC1, IC50 = 0.68 µM). It is selective for NKCC1 over NKCC2 (IC50 = 4 µM). Bumetanide is an agonist of G protein-coupled receptor 35 (GPR35, EC50 = 10 µM). It also inhibits various carbonic anhydrases. Bumetanide (0.1 mg/kg) increases urine flow and sodium and...
Keywords: | PF 1593, Ro 10-6338, 3-(aminosulfonyl)-5-(butylamino)-4-phenoxy-benzoic acid |
Application: | NKCC1/2 inhibitor |
CAS | 28395-03-1 |
MW: | 364.4 D |
From 61.00€
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Item number: LKT-B8248.250
Bumetanide binds to Na-K-Cl co-transporter and inhibits its action.
Application: | Metabolic studies |
CAS | 28395-03-1 |
MW: | 364,42 D |
From 156.00€
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Item number: AG-CR1-3543-G005
Bumetanide is a loop diuretic that is clinically used to treat congestive heart failure. Bumetanide also exhibits anxiolytic, neuroprotective and anti-epileptic/anticonvulsant activities. Bumetanide induces hyperpolarization in kidney cells, increasing whole-cell conductance and intracellular Ca2+ levels. Bumetanide...
Keywords: | PF-1593, Ro 10-6338, 3-(Aminosulfonyl)-5-(butylamino)-4-phenoxybenzoic acid |
Application: | Na-K-Cl cotransporter inhibitor |
CAS | 28395-03-1 |
MW: | 364,4 D |
From 33.00€
*