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Item number: Cay15254-1

alpha-Cyano-4-hydroxycinnamic acid (alpha-CHCA) is an inhibitor of monocarboxylate transporter 1 (MCT1) that blocks pyruvate transport in rat heart mitochondria (IC50 = 1.5 µM). It is commonly used as a matrix to facilitate peptide ionization in matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF)...

Keywords:	CHC, NSC 173138, alpha-CHCA, 2-cyano-3-(4-hydroxyphenyl)-2-propenoic acid
Application:	Monocarboxylate transporter 1 (MCT1) inhibitor
CAS	28166-41-8
MW:	189.2 D

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alpha-Cyano-4-hydroxycinnamic acid

Item number: AG-CR1-3686-G001

Specific monocarboxylate transporter (MCT) inhibitor. Inhibits mitochondrial lactate and pyruvate transport. Decreases glycolysis. Useful agent for immunometabolism research. Exhibits antitumoral and antiangiogenic activity in gliomas in vivo, decreases glycolytic metabolism, migration and invasion. Blocks lactate...

Keywords:	alpha-Cyano-4-hydroxycinnamate, alpha-CCA, 4-HCCA, CHCA, NSC173138
Application:	Specific monocarboxylate transporter (MCT) inhibitor
CAS	28166-41-8
MW:	189.2 D

50.00€ *

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Review

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