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CVN293
CVN293

Item number: Cay40983-1

A K2P13.1/THIK1 channel inhibitor (IC50 = 49 nM), selective for K2P13.1/THIK1 over K2P6.1/TWIK2 and K2P2.1/TREK-1 channels (IC50s = >30,000 nM for both), inhibits NLRP3 inflammasome-mediated IL-1ß production in LPS-stimulated primary neonatal murine microglia (IC50 = 24 nM). Formulation: A solid. InChI:...
Keywords: 4-[7-fluoro-1-(3-pyridazinylmethyl)-1H-benzimidazol-2-yl]-1,2,5-oxadiazol-3-amine
Application: K2P13.1/THIK1 channel inhibitor
CAS 2815296-08-1
MW: 311.27 D
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