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Item number: Cay10010246-5

Glycogen synthase kinase 3 (GSK3) is a serine/threonine protein kinase that is inhibited by an assortment of extracellular stimuli including insulin, growth factors, cell specification factors, and cell adhesion. SB-216763 is a potent and selective cell permeable ATP-competitive inhibitor of GSK3alpha with an IC50...

Keywords:	3-(2,4-dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione
Application:	GSK inhibitor
CAS	280744-09-4
MW:	371.2 D

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SB216763

Item number: AG-CR1-3659-M005

Solid. Soluble in DMSO (20mg/ml) or ethanol. Potent and selective cell permeable, ATP-competitive inhibitor of GSK3alpha with an IC50 value of 34nM (and similar potency for GSK3beta), DYRK1A inhibitor (IC50=0.8µM), Stimulates glycogen synthesis in liver cells and induces beta-catenin-dependent gene transcription,...

Keywords:	3-(2,4-Dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione
Application:	Potent selective cell permeable ATP-competitive inhibitor of GSK3 inhibitor
CAS	280744-09-4
MW:	371,2 D

From 39.00€ *

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Review

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