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Item number: Cay27676-5

VUF 5574 is an antagonist of the adenosine A3 receptor (Ki = 4.03 nM for the recombinant human receptor). It is greater than 2,500-fold selective for adenosine A3 over A1 and A2A receptors. VUF 5574 (100 nM) decreases phosphorylation of ERK1/2 induced by adenosine (Cay-21232) in isolated porcine coronary artery...

Keywords:	N-(2-methoxyphenyl)-N'-[2-(3-pyridinyl)-4-quinazolinyl]-urea
Application:	Adenosine A3 receptor antagonist
CAS	280570-45-8
MW:	371.4 D

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