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Item number: Cay44120-10

MRT2359 is a molecular glue degrader of G1 to S phase transition protein 1 homolog (GSPT1). It promotes the interaction between the E3 ubiquitin ligase cereblon and GSPT1, inducing the degradation of GSPT1 and termination of protein synthesis. InChI:...

Keywords:	N-[2-fluoro-5-(trifluoromethoxy)phenyl]-carbamic acid, [2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-3-oxo-1H-isoindol-5-yl]...
Application:	Molecular glue GSPT1 (ERF3A) degrader
CAS	2803881-11-8
MW:	495.39 D

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MRT-2359

Item number: TGM-T67934-100mg

Description: MRT-2359 is a potent and orally available GSPT1 reducer with antitumour activity.MRT-2359 inhibits the growth of drug-resistant non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC) cells.MRT-2359 exhibits preferential activity in MYC-driven cell lines. Target: Apoptosis, Others. Smiles:...

CAS	2803881-11-8
MW:	495.38 D

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