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Cyano-myracrylamide
Cyano-myracrylamide

Item number: Cay35155-5

Cyano-myracrylamide (CMA) is an inhibitor of zinc finger DHHC domain-containing (zDHHC) palmitoyltransferase 20 (zDHHC20, IC50 = 1.35 µM in a cell-free assay). It selectively inhibits zDHHC20 over acyl-protein thioesterase 1 (APT-1) and APT-2 at 50 µM. CMA (5-20 µM) inhibits S-acylation of Legionella E3 ligase GobX,...
Keywords: CMA, N-(cyanomethyl)-N-tetradecyl-2-propenamide
Application: ZDHHC20 inhibitor
CAS 2801702-34-9
MW: 306.5 D
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