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Item number: Cay38802-1

CL4F8-6 is an ionizable cationic lipid (pKa = 6.14) that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs). Intravenous administration of LNPs containing CL4F8-6 and encapsulating an mRNA reporter accumulate specifically in the mouse liver. LNPs containing CL4F8-6 and...

Keywords:	7-(4-(dipropylamino)butyl)-7-hydroxytridecane-1,13-diyl bis(2-hexyloctanoate)
Application:	Ionizable cationic lipid, LNP formation
CAS	2766493-12-1
MW:	808.4 D

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CL4F8-6

Item number: TGM-T84822-10mg

Description: CL4F8-6, an ionizable cationic lipid with a pKa of 6.14, is utilized in lipid nanoparticles (LNPs) for mRNA therapeutics. When incorporated into LNPs delivering Cas9 mRNA and sgRNA, CL4F8-6 facilitates CRISPR-mediated gene knockdown in mice [1]. Target: Others. Smiles:...

CAS	2766493-12-1
MW:	808.35 D

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