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Anti-Claudin-18 Isoform2-Anti-4-1BB Bispecific Antibody (Givastomig)
Anti-Claudin-18 Isoform2-Anti-4-1BB Bispecific Antibody...

Item number: BPS-84266-1

Givastomig is a bispecific antibody (BsAb) that targets Claudin-18 Isoform2 (CLDN18.2) and 4-1BB (CD137 or TNFRSF9), and has a single Fc-domain mutation (asparagine to alanine), which eleminates Fc-effector function. It binds to the surface of activated T and NK cells. It is being investigated for the treatment of...
Keywords: CLDN18, Claudin-18
Application: ELISA, FC, FA
Host: Human
Species reactivity: human
CAS 2762499-30-7
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