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Item number: Cay44655-10

PI3K/Akt/mTOR-IN-2 is an inhibitor of the PI3K/Akt/mTOR pathway. It reduces the phosphorylation of Akt and mTOR when used at a concentration of 2 µM and decreases PI3K, Akt, and mTOR levels at 4 µM. PI3K/Akt/mTOR-IN-2 is cytotoxic to A549, BGC-823, PC3, MCF-7, and MDA-MB-231 cancer cells (IC50s = 14. 9. 9. 7. and 2....

Keywords:	Phosphatidylinositol 3-Kinase/Protein Kinase B/Mammalian Target of Rapamycin Inhibitor 2, Phosphatidylinositol...
Application:	PI3K/Akt/mTOR pathway inhibitor
CAS	2757804-89-8
MW:	285.29 D

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PI3K/Akt/mTOR-IN-2

Item number: TGM-T60564-100mg

Description: PI3K/Akt/mTOR-IN-2 is a potent PI3K/AKT/mTOR inhibitor with anticancer effects and selectivity for MDA-MB-231 cells (IC50 2.29 µM). It induces cell cycle arrest and apoptosis in cancer cells. Target: PI3K, mTOR, Akt, Apoptosis. Smiles: Fc1cc(F)cc(c1)C1OCCc2c1[nH]c1ccccc21. References: Qin J, et al....

CAS	2757804-89-8
MW:	285.29 D

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