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AZD 0095
Item number: Cay42134-10
An MCT4 inhibitor (IC50 = 1.3 nM), selectively inhibits lactate influx in NCI H358 cells (IC50 = 6.1 nM), which highly express MCT4 and do not express MCT1, over lactate influx in K562 cells (IC50 = >30 µM), which highly express MCT1 and do not express MCT4, inhibits the proliferation of NCI H358 cells (IC50 = 26...
| Keywords: | 2,5,7-trimethyl-6-[[(3R)-1-[4-[6-(4-morpholinylmethyl)-3-pyridazinyl]phenyl]-3-pyrrolidinyl]oxy]-[1,2,4]triazolo[1,5-a]pyr... |
| Application: | MCT4 inhibitor |
| CAS | 2750001-23-9 |
| MW: | 500.6 D |
From 221.00€
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AZD0095
Item number: TGM-T64378-100mg
Description: AZD0095 is a selective inhibitor of MCT4 with an IC50 of 1.3 nM. Target: Monocarboxylate transporter. Smiles: Cc1nc2nc(C)c(O[C@@H]3CCN(C3)c3ccc(cc3)-c3ccc(CN4CCOCC4)nn3)c(C)n2n1. References: Goldberg FW, et al. Discovery of Clinical Candidate AZD0095, a Selective Inhibitor of Monocarboxylate Transporter...
| CAS | 2750001-23-9 |
| MW: | 500.6 D |
From 87.00€
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