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Item number: Cay25460-1

Bosutinib-d8 is intended for use as an internal standard for the quantification of bosutinib (Cay-12030) by GC- or LC-MS. Bosutinib is an inhibitor of c-Src and Abl kinases (IC50s = 1.2 and 1 nM, respectively). It also inhibits the kinases EPHB2, TrkA, TrkB, and TXK (IC50s = 8.5, 22, 27, and 40 nM, respectively)...

Keywords:	4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methylpiperazin-1-yl-2,2,3,3,5,5,6,6-d8)propoxy)quinoline-3-carb...
Application:	c-Src and Abl inhibitor, GC-MS, LC-MS, internal standard
CAS	2733145-45-2
MW:	538.5 D

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